Coombs' Activity

INCORRECT

Question 2

This positive result will be observed in which one of the following situations?

Indirect Coombs' test where Rh- red cells are incubated with anti-human IgG.

Explanation
In an indirect Coombs' test, maternal serum (or serum in question) must first be added to Rh+ red cells before anti-human IgG (Coombs' reagent) is added.

Immunological Techniques
University of Arizona
douglas.lake@asu.edu